Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11058)
Related Products (11058)
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Resveratrol-13C6
0 ImagesCat. No.: HY-16561S1Synonyms: trans-Resveratrol-13C6; SRT501-13C6Resveratrol-13C6 is the 13C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator. Resveratrol is a potent pregnane X receptor (PXR) inhibitor. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model. Resveratrol increases production of NO in endothelial cells.
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Carboxyphosphamide Benzyl Ester-d4
0 ImagesCat. No.: HY-W738320CAS No.: 1276302-73-8Carboxyphosphamide Benzyl Ester-d4 is the deuterium labeled Benzyl 3-((amino(bis(2-chloroethyl)amino)phosphoryl)oxy)propanoate (HY-W701421).
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Closantel-13C6
0 ImagesCat. No.: HY-17596SCAS No.: 1325559-20-3Closantel-13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
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Folic acid-13C5,15N
0 ImagesCat. No.: HY-16637S4CAS No.: 2687960-47-8Synonyms: Vitamin B9-13C5,15N; Vitamin M-13C5,15N
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TML-6-d3
0 ImagesCat. No.: HY-137315SCAS No.: 2673270-28-3
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Descarboethoxyloratadine-d6 diacetate
0 ImagesCat. No.: HY-154787SDescarboethoxyloratadine-d6 diacetate is deuterated labeled Descarboethoxyloratadine.
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7-Methylguanosine-13C,d3 iodide
0 ImagesCat. No.: HY-122524AS7-Methylguanosine-13C,d3 iodide is the 13C- and deuterium labeled 7-Methylguanosine iodide (HY-122524A). 7-Methylguanosine iodide is an iodide of 7-Methylguanosine (HY-122524). 7-Methylguanosine is a modified nucleoside widely present in various RNAs and a key metabolite of the 5'-cap structure of eukaryotic mRNA. 7-Methylguanosine plays important roles in stabilizing RNA structures, regulating translation, and other aspects.
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N1, N10-Diacetyl triethylenetetramine-d8
0 ImagesCat. No.: HY-143801S1N1, N10-Diacetyl triethylenetetramine-d8 is the deuterium labeled N1, N10-Diacetyl triethylenetetramine.
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4-(4-Aminophenyl)-3-morpholinone-d4
0 ImagesCat. No.: HY-W741338CAS No.: 1329837-80-04-(4-Aminophenyl)-3-morpholinone-d4 is the deuterium labeled 4-(4-Aminophenyl)morpholin-3-one (HY-50187).
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(R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3
0 ImagesCat. No.: HY-W744223(R)-10-Monohydroxy-10,11-dihydro Carbamazepine-d3 is the deuterium labeled (R)-10-Monohydroxy-10,11-dihydro Carbamazepine (HY-W739854).
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Sacubitril-13C4
0 ImagesCat. No.: HY-15407S3Synonyms: AHU-377-13C4Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19.
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Sodium 1H,1H,2H,2H-perfluoro hexanesulfonate-13C2
0 ImagesCat. No.: HY-W750530CAS No.: 2708218-88-4Sodium 1H,1H,2H,2H-perfluoro hexanesulfonate-13C2 is the 13C-labeled Sodium 1H,1H,2H,2H-perfluoro octanesulfonate.
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L-(+)-Lyxose-13C-1
0 ImagesCat. No.: HY-N0059AS1L-(+)-Lyxose-13C-1 is the 13C labeled L-Lyxose.
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L-Asparagine-4-13C monohydrate
0 ImagesCat. No.: HY-N0667S4CAS No.: 286437-12-5Synonyms: (-)-Asparagine-4-13C monohydrate; Asn-4-13C monohydrate; Asparamide-4-13C monohydrateL-Asparagine-4-13C monohydrate is the 13C-labeled L-Asparagine monohydrate (HY-W017443).L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
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Fexofenadine-d10
0 ImagesCat. No.: HY-B0801S3CAS No.: 1215900-18-7Fexofenadine-d10 is deuterium labeled Fexofenadine.
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Fosaprepitant-d4 dimeglumine
0 ImagesCat. No.: HY-14407ASSynonyms: MK-0517-d4; L785298-d4Fosaprepitant-d4 (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).
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Trihexyphenidyl-d5
0 ImagesCat. No.: HY-B1277ASTrihexyphenidyl-d5 is deuterium labeled Trihexyphenidyl (HY-B1277A). Trihexyphenidyl is a selective and orally active M1 muscarinic receptor antagonist with an IC50 of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl can be used for the research of Parkinson's disease..
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Bis(2-propylheptyl) phthalate-d4
0 ImagesCat. No.: HY-W423530SCAS No.: 1346601-46-4Synonyms: Phthalic acid bis(2-propylheptyl) ester-d4Bis(2-propylheptyl) phthalate-d4 (Phthalic acid bis(2-propylheptyl) ester-d4) is a deuterium labeled compound.
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Simvastatin-d11
0 ImagesCat. No.: HY-17502SCAS No.: 1002347-74-1Synonyms: MK 733-d11Simvastatin-d11 is the deuterium labeled Simvastatin. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM.
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Ac-rC Phosphoramidite-15N
0 ImagesCat. No.: HY-W042357SCAS No.: 1799795-94-0Ac-rC Phosphoramidite-15N is 15N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
